Health

Scientists decipher 3D structure of a promising molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment. The team has successfully determined the 3D structure of human ATP-citrate lyase (ACLY) — which plays a key role in cancer cell proliferation and other cellular processes — for […]

Health

How Enterococcus faecalis bacteria causes antibiotic resistant infection

A new study led by a research team from Massachusetts Eye and Ear and Harvard Medical School describes how bacteria adapted to the modern hospital environment and repeatedly cause antibiotic-resistant bloodstream infections. Infections acquired by hospitalized patients are more often antibiotic-resistant than those that occur elsewhere, and hospitals invest considerable effort to prevent them. Despite […]